5.
Phytochemical, Antioxidant and Cytotoxicity Properties of
Anchomanes Difformis (bl.) Engl. Tuber Extract
Idowu Doyinsola, Adebiyi Adedayo, Olajide
Olutayo, Afolayan Michael, Orishadipe Abayomi*, Omojola Moses
and Sunday Thomas
Chemistry Advanced Laboratory, Sheda Science and Technology
Complex, Sheda- Abuja, FCT, Nigeria. *Corresponding author (tayowumi_05@yahoo.co.uk
)
Abstract:
During the past two decades, there has been an increasing
interest in the investigation of different extracts obtained
from traditional medicinal plants as potential sources of potent
drugs or supplements for the management of human and animal
health. The phytochemical, antioxidant and cytotoxicity of the
extracts of Anchomanes difformis tuber were examined. The
proximate analysis of the tuber was found to contain
carbohydrates 63.64 %, protein 1.31 %, fat 1.5 %, crude fibre
content 12.3 %, ash content 6.75 % and moisture content 14.5 %.
The two extracts tested negative for saponins, resins,
terpenoids, phenols, balsam, anthracene, anthraquinone, while
the ethanol extract tested positive for alkaloids, tannins,
sterols, phlobatannins and volatile oils. The antioxidant
activity LC50 of 2.64 mg/ml, 1.82 mg/ml and 0.14 mg/ml were
recorded for the hexane, ethanol extracts and Vitamin C
respectively. The cytotoxicity result showed that both extracts
exhibited LC50 of less than 1000 mg/ml with aid of Finney
computer programming.
Keywords: Anchomanes, difformis, phytochemical,
antioxidant, cytotoxicity, Artemia salina
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