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13.
Microbial Studies of New Substituted Benzothiazolyl Bearing
Quinazolin-4(3H) Ones
N. B.
Patel*, J. N. Patel & R. C. Chaudhari
Department of Chemistry, Veer Narmad South Gujarat University, Surat
– 395 007 (INDIA), e.mail- drnavin@satyam.net.in
Abstract:
A new
class of forty-eighth Benzothiazolyl quinazolinone 1-48 were
prepared from 2-[2-(2,6-dichlorophenyl)amino]phenylmethyl-3,1-substitutedbenzoxazine-4(H)one
IIIa,b on nucleophilic reaction with different amine. The
structures of isolated compounds have been investigated on the
basis of elemental analysis, IR and 1H-NMR spectra.
The synthesized compounds were screened for antibacterial and
antifungal activity. Some of the compounds showed good
antibacterial as well as antifungal activity.
KEY WORDS:
Quinazolinone,
benzothiazole, antibacterial, antifungal.
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