ABSTRACT

The conformational analyses of some different substituted 2-aryl-trans-decahydro-quinolin-4-ols were studied by using 1H NMR spectral data. The spectral data indicated that the compounds predominantly exist in twin chair conformation and the fusion of the decalin ring system is trans. The coupling constants between the vicinal protons were used to assign the conformations of these compounds. The aryl group present at C-2 and the alkyl group present at C-3 were assigned to occupy equatorial position. The signals for N-H protons could not identified due to faster exchange of protons.