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SYNTHESIS AND STRUCTURAL STUDIES ON TRANSITION
METAL COMPLEXES DERIVED FROM 2- METHYL PROPANAL-1H-
BENZIMIDAZOL-2YL-HYDRAZONE
M. Neelamma, P. Venkateswar Rao* and V. Jyothi
Department of Chemistry, P. G. College of Science,
Saifabad, Hyderabad-500 004, A.P., India.
E. Mail:
pallapothulav@yahoo.com
pallapothulav@gmail.com
ABSTRACT
Transition metal complexes of Cr (III), Fe
(III), Mn (II), Co (II), Ni (II), Cu (II) and Zn (II) with a bidentate
ligand derived from the condensation of 2-hydrazine benzimidazole and
isobutyraldehyde (MPBH) were synthesized. Characterization has been
done on the basis of analytical, conductance, thermal and magnetic,
infrared, 1H NMR, electronic, mass and ESR spectral data.
From analytical, conductance and other physico chemical data, the
tachometry of the complexes has been found to be 1:1 (metal to
ligand). The general formula of the divalent complexes is [MLCl2
(H2O)2] and trivalent complexes is [MLCl3H2O],
where L = MPBH. Infrared spectral data suggest that the ligand MPBH
behaves as a neutral bidentate ligand with N: N donor sequence. On
the basis of the above physico chemical data, it is proposed that all
the complexes were assigned octahedral geometry. The ligand and the
metal complexes were screened for their physiological activities
against E.coli and S.aureus. The order of the activity has been
found to be Mn (II) > Fe (III) > Co (II) > Ni (II) > Cr (III) > Cu
(II) > MPBH against E.coli and Mn (II) > Fe (III) > Co (II) > Ni (II)
> Cu (II) > Cr (III) > MPBH with respect to S.aureus.
Keywords: 2-Methyl
propanal-1H-benzimidazol-2yl-hydrazone, Isobutyraldehyde, 2-Hydrazine
benzimidazole, physiological activity.
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